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In the present study has been conducted on p-Anisic acid and its application in biological systems. The high performance liquid chromatography has been used to analyse the effect of p-anisic acid. The principal moment of inertia & thermodynamic functions were calculated by adopting the following procedure of formulae by using spectroscopic data & structural parameters. The studies related to the realease of p-anisic acid from both (p-AA-CH2-HP)n oligoester (a) and [(p-AA-CH2-HP)x-co-(HB)y] (co)oligoesters (b) were performed in water solution. Biological comparioson of in vitro studies presented that the synthesized (co)oligoesters were found to non-toxic in nature non-toxic and were found to tolerant by the HaCaT cells. Both (homo) and (co)oligoesters showed a positive effect on keratinocyte growth, specifically at moderate concentrations.

Keywords

Biological System; Oligoesters; Spectroscopcy; Non-toxic; HaCaT cells

1. Basu Partha, Ghosh, Grove, Barchowsky (2008) Environmental Health Perspectives Vol. 116: No.4


2. Singh BP, Singh RS (1977) Indian Journal of physics 51B, 99-107, Vol 51-60


3. C.R. Tindale, F.B. Whitfield, S.D. Levingston, T.H.L. Naguyen, J. of the science of food and Agricultural, Vol. 49(4), 437(2006)


4. MIller, Swanson, Philips, Fletcher, Liem, J.A. Miller, Cancer Res., 43, 1124 (1983)


5. H.E. Jacob, E. Golvinsky, Z.Allg. Mikrobiol, 23:495 (1983)


6. M.P. Singh, Ph.D Thesis C.C.S. University (2003)


7. J.M. Mason, J.S. Yoon, R. Valencia, R.C. Woodruff and S.Zimmering, Environmental and molecular Mutagesis Vol. 14 (1989)


8. K.S. Jain, T.S. Chitre, P.B. Miniyar, Biological and medicinal signeficane of pyrimidines vol. 90 (2006)


9. Krzysztof Felczak, Barber, Rode, David Shugar, Maria (1998) Acta-Biochim Pol.


10. J. Axelrod, Biochemistry. J. 63, 634(1956)


11. A.J. Quick, J. Bio. Chem. 97, 403(1932)


12. A Niewiadomy, Elzbieta Krajewska, Lukaszuk, Joanna Matysiak (2005) Pub Med, 50 Suppl 1:31-35 PMID:16119621


13. C. Fuerer, R Lggo (2004) Gene Therapy 11, 142-151.


14.  Anthony, Cold well, Hutt and Smith, Food Chem. Toxicol, 25, 799 (1987)


15. Sangster, Calwell, Hutt, Anthony, Smith, Xenobiotics, 17, 1223 (1987)


16. Randerath, Hagland, Philips, Reddy, Carcinogenesis, 5, 1613 (1984)


17. Wiseman, Fennel, Miller-J.A. Miller –F.C., Cancer Res. 45, 3096 (1985)


18. Saray Quintero-Fabian, Multidisciplinary Research Laboratory, Mexico City (1997)


19. Rodrigo Arreola Psychiatric Genetics Dept. National Institute of Psychiatry, Mexico.


20. Enrique Becerril-Villanueva, Psychoimmunology Laboratory, National Institute of Psychiatry, Mexico.


21. Balzarni, J., and E.De Clercq. (1994), Biochemical pharmacology of nucleoside analogs active against HIV, P.751.772.


22. Balzarini. J., L. Naesens,. P. Herdewijn, I. Rosenberg, A. Holy, R. Rouwels, M. Baba, D.G. Johns, (1989)


23. Marked in Vivo anti retrovirus activity, Proc-Natl. Acad. Sci. USA 86:332-336.


24. Balzarini, J., Z W, P. Here P. Herdewijn, D.G. Johns and E. De Clercq (1991) Intracellular metabolism and mechanism of anti-retrovirus action of adenine derivative, Proc. Natt. Acad Sci. USA 88; 1499-1503


25. Barbons, M.C. Carthy chemical Abstract, 86:5196d(1957)


26. Bray, H.G., Lake, Thorke and White, Biochem. J., 47, p.xiii (1950)


27. H.I. Wahbi, C. Ishak, A. Khalid, T. Adlan, Int. J. Pharm Phytopharmacol. Res, (2014) 4(1), 13-19.


28. Rajiv Sharma, Good manufacturing practices for 1514 pharmaceuticals. Science Technology, entrepreneur, 10 (18), 6 (1990)


29. Pranav Jain, Ph.D Thesis (Chem), Bhopal Univ. Bhopal (1988)


30. Mikhail Tsvet (1906) Berichte der deutschen botanischen Gesellschaft




 
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