Journal Press India^®

Author Details ( * ) denotes Corresponding author

Polycystic ovary syndrome (PCOS) is a common gynecological endocrine disorder that causes reproductive and metabolic disturbances. PCOS is more common in females who have obesity and it can also be a genetic disorder in some females. During a study on teen age 17-19 years aged girls in Thailand, the prevalence rate of PCOS syndrome was 5.29 %. While, the studies in Iran had shown the prevalence rate to be 8.3% to 11.4% (Naz et al, 2019). PCOS can be treated by allopathic medicines but they have number of side effects in women like acne and menstrual irregularity. Therefore, in this study an alternative solution has been taken to prevent PCOS by the application of herbs. In this study, 7 samples of herbs were considered. Sample of Cinnamon (dalchini) was collected from a field of Punjab Agriculture University Ludhiana; Curcuma longa (turmeric), Mentha piperita (pippermint) and Allium sativum (garlic) were taken from Gurudwara Bhora Sahib (Jagraon); Ocimum sanctum (tulsi), Azadirachta indica (neem) and Casearia esculanta (saptrangi) were collected from Farm house of CT university campus (Mullanpur). These samples were dried for 48 hours at temperature 38˚C. The process of solvent extraction was used to extract the active components. To identify the extracted constituents from herbs, thin layer chromatography (TLC) was done. Some biochemical tests were performed, to confirm the presence of the identified components. From these 7 samples the active components that were successfully identified were cinnamaldehyde, allicin, estradiol and diterpenoids, alkaloids and flavonoids. These components will be further used for the preparation of herbal medicine against

Keywords

Polycystic Ovary Syndrome; Estrogen hormone; Obesity; Insulin resistance; Herbs and Solvent extraction

1. Hadi A, Moradi S, Ghavami A, Khalesi S, Kafeshani M (2020). Effect of probiotics and synbiotics on selected anthropometric and biochemical measures in women with polycystic ovary syndrome: a systematic review and meta-analysis. European Journal of Clinical Nutrition. 74: 543-547. https://doi.org/10.1038/s41430-019-0434-9


2. Ybarra M, Franco RR, Cominato L, Sampaio RB, Sucena da Rocha SM, Damiani D (2018). Polycystic Ovary syndrome among obese adolescents. J Gynecol Endocrinol. 34: 45–48.


3. Ding T, Hardiman PJ, Petersen I, Wang FF, Qu F, Baio G (2017). The prevalence of polycystic ovary syndrome in reproductive-aged women of different ethnicity: a systematic review and meta-analysis. Oncotarget. 8: 96351–96358.  


4. Naz1 M, Tehrani F, Hamid A, Fazlollah A, Giti O, Farzaneh R, Vida G. The prevalence of polycystic ovary syndrome in adolescents: A systematic review and meta-analysis International Journal of Reproductive BioMedicine, 17, Issue no. 8


5. Rashidi H, Tehrani F, Bahri M, Tohidi M, Azizi F. To what extent does the use of the Rotterdam criteria affect the prevalence of polycystic ovary syndrome? A community-based study from the Southwest of Iran. Eur J Obstet Gynecol Reprod Biol 2014; 174: 100–105.


6. Ganie M, Vishnu V, Imtiyaz A, Mohammad S, Tasleem A & Aafia R. Epidemiology, pathogenesis, genetics & management of polycystic ovary syndrome in India Indian J Med Res 150, October 2019, pp 333-344


7. Dr. Padmalaya Rath A case of infertility due to PCOS treated successfully with homoeopathyInternational Journal of Homoeopathic Sciences 2020; 4(2): 249-260


8. Misra, A.; Pachauree, S. (2002) Retention Behavior of Metal Ions on Calcium Sulphate Layers: Separation of Mercury. Ind. J. Chem. Technol., 9, 239-244.


9. Rakhi A, Jai R. Screening for Mercury in Aqueous Environmental Samples and Urine Samples Using Thin Layer Chromatography 79, 2457 (2007).  


10. Bhatia S, Kalpana N, Tanmoy B, Ajay S, Kiran S.Evaluation of pharmacognostical, phytochemical and anti-microbial properties of Porphyra vietnamensisDOI: 10.4103/0973- 8258.155065  


11. Sanguri S, Kapil S, Gopinathan P, et al. Comparative screening of antibacterial and antifungal activities of some Weeds and medicinal plants leaf extracts: An in-vitro study. Elixir Applied Botany. 2012; 47:8903-8905.  


12. Paul S and Sainsburg D. Dictionary of Microbiology and Molecular Biology. 2nd Edition. John Wiley and Sons Publishers Brisbane. 1996; 46.


13. Thapar P and Garcha S. Incidence and characterization of Pseudomonas isolated from spoiled fresh produce. Indian Journal of Experimental Biology. 2017; 55:372-376.


14. Bashir A, Sayed El H, Amiri HM. Antimicrobial activity of certain plants used in the folk medicine of United Arab Emirates. Fitoterapia. 1992; 4:371-375.


15. Marka R, Samatha T, Srinivas P, Shyamsundarachary R, Rama S. N.* Preliminary Phytochemical Analysis of Leaf, Stem, Root and Seed Extracts of Arachis hypogaea L. Int. J. Pharm. Sci. Rev. Res., 20(1), May-june 2013





 
16.  
17.  
18.