Spectral and Biological analysis of Thieno [2, 3-d] pyrimidin-4-one

Rovin; Dharmendra Kumar; Vikas Kumar; Leeladhar Singh

doi:https://doi.org/10.51976/ijari.421601

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Spectral and Biological analysis of Thieno [2, 3-d] pyrimidin-4-one

Rovin , Dharmendra Kumar, Vikas Kumar, Leeladhar Singh

Vol 4 , Issue 2 , April - June 2016 | Pages: 1-5 | Research Paper

https://doi.org/10.51976/ijari.421601

Received: January 20, 2016 | Revised: February 10, 2016 | Accepted: February 28, 2016 | Published Online: March 15, 2016

Author Details ( * ) denotes Corresponding author

1. Rovin Department of Physics, Monad University, Ghaziabad, Uttar Pradesh, India

2. * Dharmendra Kumar, Department of Applied Physics, IIMT Engineering College, Meerut, Uttar Pradesh, India (drdksisodia@gmail.com)

3. Vikas Kumar, Department of Applied Chemistry, IIMT Engineering College, Meerut, Uttar Pradesh, India

4. Leeladhar Singh, Department of Physics, Monad University, Ghaziabad, Uttar Pradesh, India

Thieno [2,3-d] pyrimidin-4-one is synthesized by 2-amino-3-carboethoxythiophene and fomamide and its structure was also established using FTIR, UV-Vis and 1H-NMR spectroscopic method. The synthesized compound was also tested for antimicrobial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus and fungus Candida albican, Aspergillus niger and Candida krusei.

Keywords

FTIR; NMR; Raman Spectroscopy; UV-Visible Spectroscopy; Pyrimidin-4-One; Antimicrobial Activity

El-Sayed WA, Ali OM, Zyada RA, Mohamed AA, Abdel-Rahman AA.Acta Pol Pharm. 2012, 69(3), 439-47.

Vikas Kumar, Pratibha Singh Der Pharma Chemica, 2010, 2(3),52–62.

el-Kerdawy MM, Yousif MY, el-Emam AA, Moustafa MA, el-Sherbeny MA. Boll Chim Farm. 1996, 135(5),301-5.

Ola H. Rizk, Omaima G. Shaaban , Ibrahim M. El-AshmawyEuropean Journal of Medicinal Chemistry 2012, 55, 85–93.

Shaaban MA, Ghorab MM, Heiba HI, Kamel MM, Zaher NH, Mostafa MI. Arch Pharm (Weinheim). 2010, 343 (7), 404-10.

Eman Z. Elrazaz, Rabah A.T. Serya, Nasser S.M. Ismail, Dalal A. Abou El Ella, Khaled A.M. Abouzid, Future Journal of Pharmaceutical Sciences, 2015, 1(2), 33–41.

Wardakhan WW, Abdel-Salam OM, Elmegeed GA. Acta Pharm. 2008, 58(1):1-14

Jameel Ahmed S. Mulla, Mohammed Iqbal A. Khazi, Shridhar I. Panchamukhi, Young-Dae Gong ,Imtiyaz Ahmed M. Khazi Medicinal Chemistry Research 2014, 23(6), 3235-3243.

A. El-Mekabat Chemistry of Heterocyclic Compounds2015, 50, (12), 1698-1706.

Krishnamurthy, B., Vinaya, K., Rakshith, D. Prasanna, D. S. Rangappa, K. S., Medicinal chemistry 2013, 9 (2), 240-248.

O. V. Svaljavyn,, M. Yu. Onysko , A. V. Turov, Yu. G. Vlasenko, V. G. Lendel Chemistry of Heterocyclic Compounds. 2013, 49(3) 491-495.

Abdel-Rahman B.A. El-Gazzar, , Hend N. Hafez, Bioorganic & Medicinal Chemistry Letters2009, 19(13), 3392–3397

Sert, Yusuf and Mahendra, M. and Shivashankar, K. and Puttaraju, K. B. and Doğan, H. and Cırak, C. and Ucun, Fatih Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014 128.109-118.