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Spectral and Biological Investigation of 5-Phenyl-1,3,4-Oxadiazole-2-Thiol
Vol 5 , Issue 1 , January - March 2017 | Pages: 69-73 | Research Paper
Received: January 25, 2017 | Revised: February 20, 2017 | Accepted: February 28, 2017 | Published Online: March 15, 2017
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In the current study, a compound 5-phenyl-1,3,4 -oxadiazole-2-thiol was synthesized by converting variously benzoic acids successively into the corresponding esters, hydrazides. The structure of the synthesized compound was confirmed based on 1H-NMR, IR, UV-Vis and mass spectral data. The synthesized compounds were screened for antimicrobial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus and fungus Candida albican, Aspergillusniger and Candida krusei.
Keywords
FTIR, NMR; Raman Spectroscopy; UV-Visible Spectroscopy; 1,3,4-Oxadiazole; Antimicrobial Activity.
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